Search results for " AIG"
showing 10 items of 15 documents
Incidence de l’endophtalmie aiguë postopératoire après chirurgie de la cataracte par phacoémulsification et injection intracamérulaire d’antibiotique…
2016
National audience; Introduction La chirurgie de la cataracte est l’intervention la plus fréquente dans le monde. Parmi ses complications, l’endophtalmie aiguë postopératoire (EAPO) est une infection intraoculaire sévère, qui peut conduire à la cécité. Les objectifs étaient de déterminer l’incidence de l’EAPO après chirurgie de la cataracte par phacoémulsification en France de 2005 à 2014 et d’analyser l’association entre injection intracamérulaire d’antibiotique (IICA) et EAPO. Méthodes Tous les patients hospitalisés pour une chirurgie de la cataracte en France entre le 1er janvier 2005 et le 31 décembre 2014 ont été identifiés dans le programme de médicalisation des systèmes d’information …
Eliminación de metales pesados en aguas mediante bioadsorción. Evaluación de materiales y modelación del proceso.
2010
Una de las principales fuentes de contaminación de las aguas es el vertido de efluentes insuficientemente depurados, razón por la que el control de vertidos ha centrado gran parte de las actuaciones legislativas de las administraciones competentes en esta materia. Las técnicas convencionales de depuración de metales pesados presentan dificultades para lograr el cumplimiento de los límites de vertido siendo necesaria la búsqueda de técnicas alternativas para reducir estas emisiones. En este sentido, la investigación en bioadsorción ha mostrado en los últimos años el potencial de esta tecnología para el tratamiento de aguas contaminadas por metales pesados. El objetivo de la tesis doctoral es…
SINDROME DA ATTIVAZIONE MACROFAGICA SECONDARIA AD IMMUNODEFICIT
2018
Introduzione: la sindrome da attivazione macrofagica (SAM) è una condizione clinica rara, di cui esistono forme primitive (es. deficit di perforine) e secondarie ad infezioni, farmaci, immunodeficit; nel 10% dei casi rappresenta una complicanza dell'artrite idiopatica giovanile sistemica (AIG). Criteri diagnostici: febbre, epatosplenomegalia, citopenia bilineare, aumento di ferritina, transaminasi, ipertrigliceridemia ed ipofibrinogenemia con segni di emofagocitosi all'aspirato midollare. Terapia: metilprednisolone a 30 mg/Kg/die ev e terapia della patologia di base; nei no-responders trova impiego l'uso dei farmaci immunosoppressori come ciclosporina, Anakinra per forme secondarie ad AIG, …
Energies Renovables i el seu Condicionament
2017
El document forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València La matèria “Energies Renovables i elassignatura amb el mateix nom i forma part del bloc comú de matèries pròpies de la branca de Telecomunicacions. S'imparteix en el primer quadrimestre del tercer curs de les titulacions de Grau en Enginyeria Electrònica de Telecomunicació i Grau en Enginyeria Telemàtica i com assignatura optativa al quart curs del Grau en Engineria Electrònica Industrial. La càrrega lectiva total és de 6 ECTS. La càrrega de treball per a l’estudiant és de 150 hores al llarg del quadrimestre, de les quals 60 són presencials i 90 són de …
Silent and symptomatic atrial fibrillation,during the acute phase of myocardial infarction : determinants and role of arginine methylated and oxidati…
2015
Atrial fibrillation (AF) is a frequent complication of acute myocardial infarction (AMI) with a poorer prognosis. Silent atrial fibrillation has been suggested to be frequent after AMI. However, most part of the studies has targeted only paroxysmal or persistent AF. Thus, Reduced Nitric Oxide availability and endothelial dysfunction has been recently recognized as a possible contributor to altered prognosis in AF. Asymmetric dimethylarginine (ADMA) can inhibit nitric oxide synthase and leads to endothelial dysfunction, inflammation and oxidative stress in multiple cardiovascular diseases. However, any study has addressed the relationship between ADMA levels and the occurrence of AF in AMI.W…
Chirurgie cardiaque sous circulation extra-corporelle et ses biomarqueurs : rôle du Growth / Différentiation Factor 15 (GDF 15) : études cliniques
2016
Ischemic cardiac diseases are the most frequent and deleterious pathologies leading to important cardiovascular-related mortality worldwide. One of the alternative therapies consists to treat these patients using cardiac surgery. Cardiopulmonary bypass was developed to greatly improve this surgical procedure. However, some adverse effects can occur during cardiac surgery associated with cardiopulmonary bypass due to the inflammatory response. This phenomenon is the result of various mechanisms including oxidative stress and inflammatory cytokines which lead to multi-organ failure and then to myocardial and renal injuries occurring during the peri- and post-operative periods.The first part o…
Role of the protein phosphatase CD45 and lipid rafts in the maintenance of acute myeloblastic leukemiaand development of a new therapeutic treatment
2017
CD45 is a pan-leukocyte protein with tyrosine phosphatase activity involved in the regulation of cytokinereceptors in hematopoiesis, such as the GM-CSF. We report here on new chemical compound,Pyrido[4,3-b]quinoxaline (PyQ), which is a plasma membrane disrupting agent, as a potential drug fortreatment of acute myeloid leukemia (AML). Indeed, we show that the hematopoietic cell lines aremore sensitive to PyQ, compared with non- hematopoietic cell lines. Using HOXA9-MEIS1-transformed blasts from a mouse model to study AML and human primary AML samples, wediscovered that CD45, which is mainly found within plasma-membrane lipid rafts, is rapidly delocalizedafter treatment with PyQ compound. The…
Cardiac rehabilitation and 5-year mortality after acute coronary syndromes: The 2005 French FAST-MI study.
2016
IF 2.271; International audience; Background. - Clinical studies have shown a beneficial effect of cardiac rehabilitation (CR) on mortality.Objective. - To study the effect of CR prescription at discharge on 5-year mortality in patients with acute myocardial infarction (AMI).Methods. - Participants, from the 2005 French FAST-MI hospital registry, were 2894 survivors at discharge, divided according to AMI type: ST-segment elevation myocardial infarction (STEMI; n=1523) and non-STEMI (NSTEMI; n=1371). The effect of CR prescription on mortality was analysed using a Cox proportional hazards model.Results. - At discharge, 22.1% of patients had a CR prescription. Patients referred to CR were youn…
Prolongation du séjour hospitalier dans un service de gériatrie aiguë : identification et analyse des causes
2016
International audience; In France, the population of very old frail patients, who require appropriate high-quality care, is increasing. Given the current economic climate, the mean duration of hospitalization (MDH) needs to be optimized. This prospective study analyzed the causes of prolonged hospitalization in an acute geriatric care unit. Over 6 months, all patients admitted to the target acute geriatric care unit were included and distributed into two groups according to a threshold stay of 14 days: long MDH group (LMDHG) and short MDH group (SMDHG). These two groups were compared. 757 patients were included. The LMDHG comprised 442 with a mean age of 86.7 years, of whom 67.65% were wome…
SINDROME DA ENCEFALOPATIA POSTERIORE REVERSIBILE: TEMIBILE COMPLICANZA IN CORSO DI MAS DA AIG SISTEMICA
2018
Background: La sindrome da encefalopatia posteriore reversibile (PRES) è un disordine secondario a diverse condizioni cliniche, caratterizzato da cefalea acuta o subacuta, nausea, vertigini, alterazioni della coscienza, convulsioni, disturbi visivi transitori, emorragia retinica ed edema del nervo ottico. Alla RMN si riscontra edema vasogenico nell'emisfero cerebrale posteriore e talvolta aree necrotiche. Riportiamo il caso clinico di una paziente con sindrome da attivazione macrofagica (MAS) secondaria ad AIG sistemica che ha sviluppato una PRES. Caso Clinico: Una adolescente di 11 anni giunge alla nostra osservazione per comparsa di febbre persistente da 10 gg. Durante la degenza è stata …